Dynein light chain 8 (LC8) interacts with intrinsically disordered proteins (IDPs) and influences a wide range of biological processes. It is becoming apparent that among the numerous IDPs that interact with LC8, many contain multiple LC8-binding sites.
“Dopamine is commonly referred to as the ‘feel-good chemical,’ due to a pathway called the mesolimbic dopamine system—the most important reward pathway in the brain,” said Dr. Kevin Ahern, Professor of Biochemistry and Biophysics at OSU
In this work, we examine the molecular role LC8 plays in viral lethality. We show that RavP and LC8 colocalize in rabies infected cells, and that LC8 interactions are essential for efficient viral polymerase functionality.
Compounds from hops may combat metabolic syndrome by changing the gut microbiome and altering the metabolism of acids produced in the liver, new research by Adrian Gombart, professor of biochemistry and biophysics, suggests.