Publications

From the Hagen group:

Bobe G, Michels A.J, Zhang W, Purnell J.Q, Woffendin C, Pereira C, Vita J.A, Thomas N.O, Traber M.G, Frei B, and Hagen T.M. (2020).

A Randomized Controlled Trial of Long-Term (R)-α-Lipoic Acid Supplementation Promotes Weight Loss in Overweight or Obese Adults without Altering Baseline Elevated Plasma Triglyceride Concentrations.

J Nutr. Jul 21;nxaa203. doi:10.1093/jn/nxaa203. Online ahead of print.
From the Cooley group:

Tugaeva K.V, Remeeva A, Gushchin I, Cooley R.B, and Sluchanko N.N. (2020)

Design, expression, purification and crystallization of human 14-3-3ζ protein chimera with phosphopeptide from proapoptotic protein BAD.

Protein Expr Purif. Jul 16;105707. doi: 10.1016/j.pep.2020.105707. Online ahead of print.
From the Gombart group:

Paraiso I.L, Revel J.S, Choi J, Miranda C.L, Lak P, Kioussi C, Bobe G, Gombart A.F, Raber J, Maier C.S, and Stevens J.F. (2020)

Targeting the Liver-Brain Axis with Hop-Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice.

Mol Nutr Food Res. Jul 6;e2000341. doi: 10.1002/mnfr.202000341. Online ahead of print.
From the Mehl group:

Beyer J, Hosseinzadeh P, Gottfried-Lee I, Van Fossen E.M, Zhu P, Bednar R.M, Karplus P.A, Mehl R.A, and Cooley R.B. (2020).

Overcoming Near-Cognate Suppression in a Release Factor 1-deficient Host With an Improved Nitro-Tyrosine tRNA Synthetase.

J Mol Biol. Jun 19;S0022-2836(20)30410-1. doi: 10.1016/j.jmb.2020.06.014. Online ahead of print.
From the Perez group:

Sunchu B, Riordan R.T, Yu Z, Almog I, Dimas-Munoz J, Drake A.C, and Perez V.I. (2020).

Aggresome-Like Formation Promotes Resistance to Proteotoxicity in Cells From Long-Lived Species.

J Gerontol A Biol Sci Med Sci. Jun 9;glaa069. Doi: 10.1093/gerona.glaa069. Epub ahead of print.
From the Freitag group:

Ridenour J.B, Möller M, and Freitag M. (2020).

Polycomb Repression Without Bristles: Facultative Heterochromatin and Genome Stability in Fungi.

Genes (Basel) Jun 9;11(6):E638. doi: 10.3390/genes11060638.
From the Hendrix group:

Long D.M, Frame A.K, Reardon P.N, Cumming R.C, Hendrix D.A, Kretzschmar D, and Giebultowicz J.M. (2020).

Lactate Dehydrogenase Expression Modulates Longevity and Neurodegeneration in Drosophila melanogaster.

Aging (Albany NY) Jun 2;12. doi: 10.18632/aging.103373. Epub ahead of print.
From the Perez group:

Díaz-Valdivia N.I, Díaz J, Contreras P, Campos A, Rojas-Celis V, Burgos-Ravanal R.A, Lobos-Gonzalez L, Torres V.A, Perez V.I, Frei B, Leyton L, and Quest A.F.G. (2020).

The Non-Receptor Tryosine Phosphatase Type 14 Blocks caveolin-1-enhanced Cancer Cell Metastatsis.

Oncogene Apr;39(18):3693-3709. Doi: 10.1038/s41388-020-1242-3. Epub 2020 Mar 9.
From the Mehl group:

Jang H.S, Jana S, Blizzard R.J, Meeuwsen J.C, and Mehl R.A. (2020).

Access to Faster Eukaroytic Cell Labeling with Encoded Tetrazine Amino Acids.

J Am Chem Soc. Apr 22;142(16):7245-7249. doi: 10.1021/jacs.9b11520. Epub 2020 Apr 10.
From the Gombart group:

Logan I.E, Bobe G, Miranda C.L, Vasquez-Perez S, Choi J, Lowry M.B, Sharpton T.J, Morgun A, Maier C.S, Stevens J.F, Shulzhenko N, and Gombart A.F. (2020).

Germ-Free Swiss Webster Mice on a High-Fat Diet Develop Obesity, Hyperglycemia, and Dyslipidemia.

Microorganisms Apr 5;8(4):520. doi: 10.3390/microorganisms8040520.
From the Gombart group:

Calder P.C, Carr A.C, Gombart A.F, and Eggersdorfer M. (2020).

Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect Against Viral Infections.

Nutrients Apr 23;12(4):1181. doi: 10.3390/nu12041181.
From the Beckman group:

Vimer S, Ben-Nissan G, Morgenstern D, Kumar-Deshmukh F, Polkinghorn C, Quintyn R.S, Vasil'ev Y.V, Beckman J.S, Elad N, Wysocki V.H, and Sharon M. (2020).

Comparative Structural Analysis of 20S Proteasome Ortholog Protein Complexes by Native Mass Spectrometry.

ACS Cent Sci. Apr 22;6(4):573-588. doi: 10.1021/acscentsci.0c00080. Epub 2020 Apr 10.
From the Mehl group:

Porter J.J, Jang H.S, Haque M.M, Stuehr D.J, and Mehl R.A. (2019)

Tyrosine Nitration on Calmodulin Enhances calcium-dependent association and activation of Nitric Oxide Synthase.

J Biol Chem. Feb 21;295(8):2203-2211. doi: 10.1074/jbc.RA119.010999. Epub 2019 Dec 30.
From the Nyarko group:

Kwok E, Rodriguez D.J, Kremerskothen J, and Nyarko A. (2019).

Intrinsic Disorder and Amino Acid Specificity Modulate Binding of the WW2 Domain in Kidney and Brain Protein (KIBRA) to Synaptopodin.

J Biol Chem. Nov 15;294(46):17383-17394. doi: 10.1074/jbc.RA119.009589. Epub 2019 Oct 9.
From the Estevez, Franco and Beckman group:

Strayer, A, Dennys-Rivers, C, Ricart, K, Narae, B, Beckman, J, Franco MC, Estevez, AG. (2019).

Ligand-independent activation of the P2X7 receptor by Hsp90 inhibition stimulates motor neuron apoptosis.

Experimental Biology and Medicine. 244(11):901-914.

Biochemistry and Biophysics

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A Randomized Controlled Trial of Long-Term (R)-α-Lipoic Acid Supplementation Promotes Weight Loss in Overweight or Obese Adults without Altering Baseline Elevated Plasma Triglyceride Concentrations.

Design, expression, purification and crystallization of human 14-3-3ζ protein chimera with phosphopeptide from proapoptotic protein BAD.

Targeting the Liver-Brain Axis with Hop-Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice.

Overcoming Near-Cognate Suppression in a Release Factor 1-deficient Host With an Improved Nitro-Tyrosine tRNA Synthetase.

Aggresome-Like Formation Promotes Resistance to Proteotoxicity in Cells From Long-Lived Species.

Polycomb Repression Without Bristles: Facultative Heterochromatin and Genome Stability in Fungi.

Lactate Dehydrogenase Expression Modulates Longevity and Neurodegeneration in Drosophila melanogaster.

The Non-Receptor Tryosine Phosphatase Type 14 Blocks caveolin-1-enhanced Cancer Cell Metastatsis.

Access to Faster Eukaroytic Cell Labeling with Encoded Tetrazine Amino Acids.

Germ-Free Swiss Webster Mice on a High-Fat Diet Develop Obesity, Hyperglycemia, and Dyslipidemia.

Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect Against Viral Infections.

Comparative Structural Analysis of 20S Proteasome Ortholog Protein Complexes by Native Mass Spectrometry.

Tyrosine Nitration on Calmodulin Enhances calcium-dependent association and activation of Nitric Oxide Synthase.

Intrinsic Disorder and Amino Acid Specificity Modulate Binding of the WW2 Domain in Kidney and Brain Protein (KIBRA) to Synaptopodin.

Ligand-independent activation of the P2X7 receptor by Hsp90 inhibition stimulates motor neuron apoptosis.

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