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OSU targets COVID’s N protein; research could lead to new treatments


“If we interfere with how the RNA of the N [protein] protects the RNA, then the RNA can be cleaved, can be cut into pieces, will not work and then we don’t have replication or transmission of the virus,” Barbar said.

“All the worries that we have now about variants and if the vaccine works against the variants is because we’re focusing on the S protein, but when we start focusing on the N protein, the N protein does not vary as much. So, the vaccines that are developed would have a more lasting effect,” Barbar said.