OREGON STATE UNIVERSITY
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The Barbar lab’s research is focused on the structural biology of the large dynamic molecular machines with primary focus on the dynein motor complex, rabies virus assembly, and transcription factors that bind the hub protein LC8.
Agricultural & Life Sciences
The Beckman lab works on the role of oxidative stress in ALS and other neurological diseases and discovery of new drugs to treat ALS. We are also inventing new mass spectrometry technology to better understand the basis of disease.
Agricultural & Life Sciences
Our research is focused on the role of redox signaling by reactive nitrogen species, especially tyrosine nitration as a cause of pathology in the nervous system. We aim to understand the role of redox signaling in the process of metabolic reprogramming, development, and growth of tumors of the nervous system.
Agricultural & Life Sciences
Carrie Marean-Reardon
Title: Manager 2 Research Ops
Phone: 541-737-2071
E-mail: mareanc@oregonstate.edu
The Freitag lab studies the structure of nuclei and chromosomes, using fungi as model organisms. The most recent projects involve studies on gene silencing by histone modifications and expression of promising new natural products from previously silenced gene clusters.
Agricultural & Life Sciences
Lanelle Connolly
Title: Senior Faculty Research Assistant I
Phone: 541-737-4399
E-mail: connolll@oregonstate.edu
The Gombart lab focuses on the regulation of the human antimicrobial peptide gene (CAMP) by vitamin D and plant-derived polyphenols via nuclear receptors. Our goal is to develop therapies to treat conditions like obesity, metabolic syndromes, and infections.
Linus Pauling Institute
The Hagen lab seeks to identify the mode of action of two “age-essential” micronutrients, lipoic acid and acetyl-Lcarnitine.
Linus Pauling Institute
Judy Butler
Title: Senior Faculty Research Assistant
Phone: 541-737-9953
E-mail: judy.a.butler@oregonstate.edu
The Hendrix lab studies computational biology, regulatory genomics, machine learning, and bioinformatics.
Agricultural & Life Sciences
Our laboratory is interested in studying the structural aspects of biomolecular recognition and interactions, especially in protein-nucleic acid complexes. These interactions account for many of the major cell functions such as the induction or repression of gene expression and the packaging of nucleic acids into other superstructures.
Agricultural & Life Sciences
The Johnson lab is currently focused on protein sensors of intracellular calcium and their function in membrane trafficking. Of particular interest is the protein otoferlin, which is a member of the ferlin family of proteins.
Agricultural & Life Sciences
In the McFadden lab, we are investigating how minerals accumulate in biological matrices. Our work puts us in close kinship with those who study other biomineralized systems such as bone, mollusk and echinoderm shells as well as the hardened anatomical features of many invertebrates, including rasping and cutting tools for feeding and stingers for defense.
Agricultural & Life Sciences
The Mehl Lab uses genetic code expansion to sitespecifically incorporate non-canonical amino acids (ncAAs) into proteins to advance the capabilities of biochemical studies and technological development with bio-molecules.
Agricultural & Life Sciences
Grace Galles
Title: (Courtesy) Research Assistant
Phone: 541-737-4428
E-mail: gallesg@oregonstate.edu
Subhashis Jana
Title: Research Associate (Postdoc)
Phone: 541-737-4428
E-mail: janasu@oregonstate.edu
Bio: Patrick Gleason received his Ph. D. from Arizona State University where he studied protein design with non-canonical amino acids. During his studies, he split his time equally between computational work using the Rosetta protein design software suite (as well as other software) and hands-on lab work. He truly enjoys being able to both design on the computer and then "build" in the lab.
Bio: Riley Bednar recently received his PhD here at OSU, with Dr. Mehl, developing and applying genetic code expansion technologies that enabled them to uncover the phenomena that govern the interaction of immobilized proteins at material interfaces. As a part of Riley's postdoctoral studies, he is continuing to apply genetic code expansion tools to more efficiently design and construct protein bioconjugates with greater precision and complexity using ultrafast bioorthogonal chemistry.
Savanna Avila-Crump
Title: Laboratory Technician
Phone: 541-737-4428
E-mail: avilacrs@oregonstate.edu
The Nyarko lab is engaged in projects whose longterm goal is to understand how the size of an organ is controlled. We use techniques such as NMR, and ITC to explore binding specificites, and provide molecular level insights into the regulation of proteins that promote cell growth.
Agricultural & Life Sciences
The Perez lab’s primary research focus is on the investigation of the role of protein homeostasis in aging as well as studies on investigation the mechanisms by which rapamycin extends health span and longevity.
Linus Pauling Institute
The Qiu lab is focused on understanding the mechanics of motor proteins using single-molecule light microscopy.
Agricultural & Life Sciences
