Skip to main content
A man in a white button-up gestures to molecular art on a table, explaining it to onlooking students.

Students bake, sculpt and stitch molecular structures to life in Protein Portraits colloquium

By Kallie Hagel

Honors colloquium courses provide a space where faculty can blend personal interests with professional expertise to create one-of-a-kind learning experiences and opportunities for creative exploration. These courses often bridge seemingly unrelated disciplines, and this is a hallmark of one of the most popular and frequently offered colloquium courses, Protein Portraits, taught by biochemistry and biophysics professor Phil McFadden.

In Protein Portraits, students explore protein molecules and create their own artistic renderings of their structures. Over 15 years of teaching the course, McFadden has seen tea plant necrotic ring blotch virus reimagined as a hand-stitched tea cozy, prion proteins represented in a sculpture of a moody cow, and ranasmurfin — an electric-blue protein isolated from tree frog nests — transformed into a tropical Smurf-themed layer cake.

Students admire a two-tiered, smurf-themed cake based on a blue tree frog protein.

Students admire a smurf-themed cake based on a blue protein found in tree frog nests.

Why spend ten weeks observing, discussing and inventing molecular art? Students overwhelmingly give one answer: it’s fun; but it also allows them to revisit artistic passions pushed aside when their focus in college shifted to intensive, science-based studies. While many participants are STEM majors who also sculpt, bake or crochet, other students with no artistic background embrace the chance to creatively depict a protein using any medium of their choice. McFadden’s motivation for the course is deeper.

"Art precedes science — this is important for students to understand,” he says. “No one has ever seen a molecule. Discoveries about proteins often stem from understanding their 3D structure, and we rely on molecular models — artistic renderings — to gain such knowledge.” Put another way: “We depend on art to make the invisible visible to our very thinking.”

Read more here.