Publications

From the Mehl group:

Porter J.J, Jang H.S, Haque M.M, Stuehr D.J, and Mehl R.A. (2019)

Tyrosine Nitration on Calmodulin Enhances calcium-dependent association and activation of Nitric Oxide Synthase.

J Biol Chem. Feb 21;295(8):2203-2211. doi: 10.1074/jbc.RA119.010999. Epub 2019 Dec 30.
From the Nyarko group:

Kwok E, Rodriguez D.J, Kremerskothen J, and Nyarko A. (2019).

Intrinsic Disorder and Amino Acid Specificity Modulate Binding of the WW2 Domain in Kidney and Brain Protein (KIBRA) to Synaptopodin.

J Biol Chem. Nov 15;294(46):17383-17394. doi: 10.1074/jbc.RA119.009589. Epub 2019 Oct 9.
From the Estevez, Franco and Beckman group:

Strayer, A, Dennys-Rivers, C, Ricart, K, Narae, B, Beckman, J, Franco MC, Estevez, AG. (2019).

Ligand-independent activation of the P2X7 receptor by Hsp90 inhibition stimulates motor neuron apoptosis.

Experimental Biology and Medicine. 244(11):901-914.
From the Barbar group:

Jespersen N, Barbar E.J. (2020).

Emerging Features of Linear Motif-Binding Hub Proteins.

Cell Feb 20. https://doi.org/10.1016/j.tibs.2020.01.004
From the Barbar group:

Reardon P.N, Jara K.A, Rolland A.D, Smith D.A, Hoang H.T.M, Prell J.S, and Barbar E.J. (2020)

The dynein light chain 8 (LC8) binds predominantly "in-register" to a multivalent intrinsically disordered partner.

J Biol Chem. Mar 5. pii: jbc.RA119.011653. doi: 10.1074/jbc.RA119.011653. [Epub ahead of print]
From the Merrill group:

Breysse D.H, Boone R.M, Long C.M, Merrill M.E, Schaupp C.M, White C.C, Kavanagh T.J, Schmidt E.E, and Merrill G.F. (2020)

Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified.

Drug Metab Dispos Mar;48(3):187-197. doi: 10.1124/dmd.119.089326. Epub 2020 Jan 18.
From the Hendrix group:

Kashyap A, Rhodes A, Kronmiller B, Berger J, Champagne A, Davis E.W, Finnegan M.V, Geniza M, Hendrix D.A, Löhr C.V, Petro V.M, Sharpton T.J, Wells J, Epps C.W, Jaiswal P, Tyler B.M, and Ramsey S.A. (2020)

Pan-tissue transcriptome analysis of long noncoding RNAs in the American beaver Castor canadensis.

BMC Genomics Feb 12;21(1):153. doi: 10.1186/s12864-019-6432-4.
From the Beckman group:

Williams J.P, Morrison L.J, Brown J.M, Beckman J.S, Voinov V.G, and Lermyte F. (2020)

Top-Down Characterization of Denatured Proteins and Native Protein Complexes Using Electron Capture Dissociation Implemented within a Modified Ion Mobility-Mass Spectrometer.

Anal Chem Feb 11. doi: 10.1021/acs.analchem.9b04763. [Epub ahead of print]
From the Mehl group:

Jang H.S, Gu X, Cooley R.B, Porter J.J, Henson R.L, Willi T, DiDonato J.A, Hazen S.L, and Mehl R.A. (2020).

Efficient Site-Specific Prokaryotic and Eukaryotic Incorporation of Halotyrosine Amino Acids into Proteins.

ACS Chemical Biology Feb 10. doi: 10.1021/acschembio.9b01026. [Epub ahead of print]
From the Gombart group:

Gombart A.F, Pierre A, Maggini S. (2020)

A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection.

Nutrients Jan 16;12(1). pii: E236. doi: 10.3390/nu12010236
From the Hendrix group:

Zhang Z, Garzotto M, Davis E.W 2nd, Mori M, Stoller W.A, Farris P.E, Wong C.P, Beaver L.M, Thomas G.V, Williams D.E, Dashwood R.H, Hendrix D.A, Ho E, and Shannon J. (2020)

Sulforaphane Bioavailability and Chemopreventive Activity in Men Presenting for Biopsy of the Prostate Gland: A Randomized Controlled Trial.

Nutr Cancer. 2020;72(1):74-87. doi: 10.1080/01635581.2019.1619783. Epub 2019 Jun 1.
From the Mehl group:

Porter J.J, Jang H.S, Haque M.M, Stuehr D.J, and Mehl R.A. (2019)

Tyrosine Nitration on Calmodulin Enhances calcium-dependent association and activation of Nitric Oxide Synthase.

J Biol Chem. Dec 30. pii: jbc.RA119.010999. doi: 10.1074/jbc.RA119.010999. [Epub ahead of print]
From the Barbar group:

Forsythe H.M, Vetter C.J, Jara K.A, Reardon P.N, David L.L, Barbar E.J, and Lampi K.J. (2019)

Altered Protein Dynamics and Increased Aggregation of Human γS-Crystallin Due to Cataract-Associated Deamidations.

Biochemistry Oct 8;58(40):4112-4124. doi: 10.1021/acs.biochem.9b00593. Epub 2019 Sep 26.
From the Beckman group:

Trias E, Kovacs M, King P.H, Si Y, Kwon Y, Varela V, Ibarburu S, Moura I.C, Hermine O, Beckman J.S, and Barbeito L. (2019).

Schwann cells orchestrate peripheral nerve inflammation through the expression of CSF1, IL-34, and SCF in amyotrophic lateral sclerosis.

Glia. Dec 20: doi: 10.1002/glia.23768. [Epub ahead of print].
From the Beckman group:

Shaw J.B, Liu W, Vasil Ev. Y.V, Bracken C.C, Malhan N, Guthals A, Beckman J.S, and Voinov V.G. (2019).

Direct Determination of Antibody Chain Pairing by Top-down and Middle-down Mass Spectrometry Using Electron Capture Dissociation and Ultraviolet Photodissociation.

Anal Chem. Dec 12: doi: 10.1021/acs.analchem.9b03129. [Epub ahead of print]

Biochemistry and Biophysics

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Tyrosine Nitration on Calmodulin Enhances calcium-dependent association and activation of Nitric Oxide Synthase.

Intrinsic Disorder and Amino Acid Specificity Modulate Binding of the WW2 Domain in Kidney and Brain Protein (KIBRA) to Synaptopodin.

Ligand-independent activation of the P2X7 receptor by Hsp90 inhibition stimulates motor neuron apoptosis.

Emerging Features of Linear Motif-Binding Hub Proteins.

The dynein light chain 8 (LC8) binds predominantly "in-register" to a multivalent intrinsically disordered partner.

Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified.

Pan-tissue transcriptome analysis of long noncoding RNAs in the American beaver Castor canadensis.

Top-Down Characterization of Denatured Proteins and Native Protein Complexes Using Electron Capture Dissociation Implemented within a Modified Ion Mobility-Mass Spectrometer.

Efficient Site-Specific Prokaryotic and Eukaryotic Incorporation of Halotyrosine Amino Acids into Proteins.

A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection.

Sulforaphane Bioavailability and Chemopreventive Activity in Men Presenting for Biopsy of the Prostate Gland: A Randomized Controlled Trial.

Tyrosine Nitration on Calmodulin Enhances calcium-dependent association and activation of Nitric Oxide Synthase.

Altered Protein Dynamics and Increased Aggregation of Human γS-Crystallin Due to Cataract-Associated Deamidations.

Schwann cells orchestrate peripheral nerve inflammation through the expression of CSF1, IL-34, and SCF in amyotrophic lateral sclerosis.

Direct Determination of Antibody Chain Pairing by Top-down and Middle-down Mass Spectrometry Using Electron Capture Dissociation and Ultraviolet Photodissociation.

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